Division of General Surgery

Paul C. Kuo, MD, MBA

Professor of Surgery

Division Chief, General Surgery

Department:
Surgery

Division:
General Surgery

Mailing Address:
DUMC 3522 Durham, NC 27710

Telephone:
919-668-1856

Office Telephone:
919-668-1856

Fax:
919-684-8716

Training:
MD, Johns Hopkins University School of Medicine (Maryland), 1985

Residency:
Surgery, Brigham and Women's Hospital (Massachusetts), 1991

Clinical Interests:
General, laparoscopic, hepato-biliary, and liver-, kidney-, and pancreas-transplantation surgery

Research Interests:
1. Redox regulation of inducible nitric oxide synthase gene transcription
2. Osteopontin-mediated regulation of iNOS expression

Publications:
Wu TS, Tsai YL, Damu AG, Kuo PC, Wu PL. Constituents from the Root and Stem of Aristolochia elegans. J Nat Prod. 2002 Nov;65(11):1522-5.

Wei JP, Kuo PC, Guo HT. Nitric oxide inhibits expression of electron transport proteins in endotoxin-stimulated murine macrophages. Biochem Biophys Res Commun 289: 993-7, 2002.

Wei J, Guo H, Kuo PC. Endotoxin-stimulated nitric oxide production inhibits expression of cytochrome c oxidase in ANA-1 murine macrophages. J Immunol. 2002 May 1;168(9):4721-7.

Muir AJ, Sanders LL, Heneghan MA, Kuo PC, Wilkinson WE, Provenzale D. An examination of factors predicting prioritization for liver transplantation. Liver Transpl. 2002 Oct;8(10):957-61.

Marino G, Rustgi VK, Salzberg G, Johnson LB, Kuo PC, Plotkin JS, Flockhart DA. Pharmacokinetics and biochemical effects of hepapoietin in patients with chronic liver disease. Aliment Pharmacol Ther. 2002 Feb;16(2):235-42.

Jha RC, Korangy SJ, Ascher SM, Takahama J, Kuo PC, Johnson LB. MR angiography and preoperative evaluation for laparoscopic donor nephrectomy. AJR Am J Roentgenol. 2002 Jun;178(6):1489-95.

Guo HT, Cai CQ, Schroeder RA, Kuo PC. Nitric oxide is necessary for CC-class chemokine expression in endotoxin-stimulated ANA-1 murine macrophages. Immunol Lett. 2002 Jan 1;80(1):21-6.

Guo H, Wei J, Inoue Y, Gonzalez FC, Kuo PC. Serine/Threonine Phosphorylation Regulates HNF-4{alpha} Dependent Redox Mediated iNOS Expression in Hepatocytes. Am J Physiol Cell Physiol. 2002 Dec 4;():.

Guo H, Cai CQ, Kuo PC. Hepatocyte nuclear factor-4alpha mediates redox sensitivity of inducible nitric-oxide synthase gene transcription. J Biol Chem. 2002 Feb 15;277(7):5054-60.

Buell JF, Hanaway MJ, Potter SR, Koffron A, Kuo PC, Leventhal J, Cho E, Johnson M, Edye M, Woodle ES. Surgical techniques in right laparoscopic donor nephrectomy. J Am Coll Surg. 2002 Jul;195(1):131-7.

Wai PH, Ewing CA, Johnson LB, Lu AD, Attinger C, Kuo PC. Candida fasciitis following renal transplantation. Transplantation. 2001 Aug 15;72(3):477-9.

Plotkin JS, Johnson LB, Rustgi VK, Kuo PC, Liu AD. Dobutamine stress echocardiography for orthotopic liver transplant evaluation. Transplantation. 2001 Mar 27;71(6):818.

Marroquin CE, Marino G, Kuo PC, Plotkin JS, Rustgi VK, Lu AD, Edwards E, Taranto S, Johnson LB. Transplantation of hepatitis C-positive livers in hepatitis C-positive patients is equivalent to transplanting hepatitis C-negative livers. Liver Transpl. 2001 Sep;7(9):762-8.

Kuo PC. Reconsideration of HIV as a contraindication to transplantation. Transplantation. 2001 Jun 15;71(11):1689.

Kuo PC, Stock PG. Transplantation in the HIV+ patient. Am J Transplant. 2001 May;1(1):13-7.

Kuo PC, Lu AD, Johnson LB. Expanded criteria donors/high risk recipients is not always cheaper than hemodialysis. Transplantation. 2001 Aug 15;72(3):554-5.

Guo H, Wei J, Kuo PC. Nitric oxide inhibits expression of cytochrome B in endotoxin-stimulated murine macrophages. Biochem Biophys Res Commun. 2001 Dec 21;289(5):993-7.

Guo H, Cai CQ, Schroeder RA, Kuo PC. Osteopontin is a negative feedback regulator of nitric oxide synthesis in murine macrophages. J Immunol. 2001 Jan 15;166(2):1079-86.

Cappadonna CR, Johnson LB, Lu AD, Kuo PC. Outcome of extra-anatomic vascular reconstruction in orthotopic liver transplantation. Am J Surg. 2001 Aug;182(2):147-50.

9. Wai PH, Ewing CA, Johnson LB, Lu AD, Attinger C, Kuo PC. Candida fasciitis following renal transplantation. Transplantation 72: 477-9, 2001.

8. Buell JF, Edye M, Johnson M, Li C, Koffron A, Kuo P et al. Are concerns over right laparoscopic donor nephrectomy warranted? Ann Surg 233: 645-651, 2001.

7. Kuo PC, Lu AD, Johnson LB. ECD/HRR is not always cheaper than hemodialysis. Transplantation 72: 554-555, 2001.

6. Cappadona C, Johnson LB, Lu AD, Kuo PC. Outcomes of extra-anatomic vascular reconstruction in orthotopic liver transplantation. Am J Surg 182: 147-50, 2001.

5. Kuo PC. Reconsideration of HIV as a contraindication to transplantation. Transplantation 71: 1689, 2001.

4. Guo HT, Cai CQ, Kuo PC. Endotoxin and NO induce MIP-1g gene transcription in ANA-1 murine macrophages. Biochem Biophys Res Commun 277: 617-621, 2000.

3. Kuo PC, Stock PG. Transplantation in the HIV+ patient. Am J Transplant 1: 13-17, 2001.

2. Plotkin JS, Johnson LB, Rustgi V, Kuo PC, Lu AD. Dobutamine stress echo for orthotopic liver transplant evaluation. Transplantation 71: 818, 2001.

13. Guo HT, Kuo PC. Nitric oxide is necessary for CC-class chemokine expression in endotoxin stimulated ANA-1 murine macrophages. Immunol Lett 80: 21-6, 2002.

12. Marroquin CE, Marino G, Kuo PC, et al. Transplantation of hepatitis C positive livers in hepatitis C positive recipients is equivalent to transplanting hepatitis C negative livers. Liver Trans 7: 762-768, 2001.

11. Marino G, Rustgi VK, Marroquin CE, Plotkin JS, Kuo PC, Lu AD, Johnson LB. Early recurrence of hepatitis C after liver transplantation with daclizumab induction. Am J Transplant 182: 147-150, 2001.

10. Kuo PC. Laparoscopic living donor nephrectomy. MDvista Journal of Medicine April 2001.

1. Guo HT, Cai C, Schroeder RA, Kuo PC. Osteopontin is a negative feedback regulator of NO synthesis in murine macrophages. J Immunol 166: 1079-1086, 2001.